What is Bio-Compatible Hormone Replacement Therapy?

Bio-compatible Hormone Replacement Therapy is the specific compounding of hormones to achieve a custom-fit therapy for each patient rather than a one-size-fits-all. Bio-Compatible Hormones are determined by either blood or saliva testing and then compounded to closely match the hormones your body produces naturally. They imitate the natural actions of your own internal hormone levels.

All of our compounded products are color-coded and independently tested for potency and purity so that the patient can be confident that they are receiving the correct medication in the most-beneficial strength for their needs. Our compounding pharmacists and technicians have successfully completed rigorous training programs that are designed and taught by the American College of Apothecaries and member of the International Association of Compounding Pharmacies (IACP). Each is a professional in the area of hormone-replacement therapy and is available for patient consultations. Every patient will be given a contact number for a personal consult that they can contact with any questions or concerns regarding their medication. Medi-Stat is dedicated to providing excellent customer service that constantly and consistently exceeds the customers expectations.

Your Bio-compatible Hormones will be shipped right to your door. Each medication is packaged discretely in an attractive case that you can use to carry along with you wherever you go. Here at Medi-Stat we have put a lot of thought into the packaging of your medication. It's attractive new-look design is devised to enhance consumer appeal and present a consistent high-quality image.

Benefits of BHRT:

  • Emphasis on Topical

  • Administration


  • Individualized compounded doses, rather the one dose fits all approach of conventional hormone-replacement therapy

  • Wide range of dosage forms


  • One-on-One consultation with a pharmacist

Various Dosage Forms:

  • Transdermal


  • Sublingual


  • Capsules


  • Injectables


  • Suppositories


Non-oral absorption avoids first-pass liver metabolism, providing a more-reliable extent of absorption which is independent of liver function. The slower release of hormones more closely replicates the natural production by the body.

Why are natural hormones not patented?
Same reason you cannot patent natural air, water, or vitamins. Unpatentable natural hormones can be manufactured and sold by anyone, as long as standards of purity and consistency of dose are met.

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On 1/10/2008 the US Food and Drug Administration sent letters warning seven pharmacy operations that the claims they make about the safety and effectiveness of their so-called "bio-identical hormone replacement therapy," or "BHRT" products are unsupported by medical evidence, and are considered false and misleading by the agency. The FDA is concerned that unfounded claims like these mislead women and healthcare professionals.




A large government-sponsored study of cardiovascular risk factors in women taking various estrogen/progestin replacement regimens was published in the Journal of American Medical Association. Referred to as the PEPI Trial, it confirmed the fact that synthetic progestins partially negate the beneficial effects on cholesterol levels that result from taking estrogen. Natural Progesterone, on the other hand, maintains all the benefits of estrogen on cholesterol without any side-effects associated with synthetic progestins (such as fluid retention, irritability and depression).